Canseq150 helps Canadian scientists map the Grizzly genome.
Among the largest predators in country, the Grizzly bear now has another claim to fame: the most complete genetic map for its species. Within 37 pairs of chromosomes composed of about 2.3 billion nucleotide base pairs, scientists have now revealed the location of 19,848 coding genes, 7,061 non-coding genes, 3,671 pseudo-genes, and more, within the Grizzly genome.
The Grizzly bear DNA was sequenced from a 20-year old male named Samson. He was found as an orphan in Alaska in 1998, when he was less than a year old, rescued and then raised at the Alaska Children’s Zoo. He now lives at the Toronto Zoo. The blood sample donated to the GSC was collected during a routine physical exam.
Published in the journal, Genes, the sequencing effort was performed at Canada’s Michael Smith Genome Sciences Centre at BC Cancer, a leading international centre for genomics and bioinformatics research. Dr. Steve Jones, GSC Co-Director and Head of Bioinformatics, was the Principal Investigator.
Canada’s Genomics Enterprise launchesCanSeq150 to lay the foundation for Canada’s next 150 years of science.
To commemorate the 150th Birthday of Canada in 2017 and to lay the foundation of Canadian excellence in research for the next 150 years, Canada’s Genomics Enterprise (CGEn) and its partners are embarking upon the Canada 150 Sequencing Initiative (CanSeq150). The aim is to sequence 150 new genomes to support sequence-based genomics research in Canada by enabling future research in biodiversity and conservation, applications in breeding and biomedicine, as well as technology development, across Canada.
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To support a new era of Canadian genome research, in 2014 Canada’s Foundation for Innovation (CFI) and its partners invested $58M in Canada’s Genomics Enterprise (CGEn), building an unprecedented sequencing and informatics capacity to decode genomes. CGEn linked three nationally funded centres in Toronto (The Centre for Applied Genomics), Montreal (McGill University and Genome Quebec Innovation Centre) and Vancouver (Canada’s Michael Smith Genome Science Centre). Furthermore, in 2017, an additional $32M were invested in CGEn through the CFI Major Science Initiative. CGEn, for the first time, built a coordinated framework for open access and collaborative genome sequencing across Canada.