Mark Caulfield, Genomics England interim CEO & CGEn’s Board of Directors member awarded knighthood in the Queen’s birthday honours.
Professor Mark Caulfield, the interim Chief Executive at Genomics England and Professor of Clinical Pharmacology at Queen Mary University of London, has been awarded a knighthood in the Queen’s Birthday Honours List.
Since 2013 Professor Caulfield has been instrumental in delivering the world-leading 100,000 Genomes Project, which hit its target of sequencing 100,000 whole genomes in 2018 and has already delivered life-changing results for patients.
This NHS transformation programme used whole genome sequencing to bring new diagnoses to people with rare diseases and to help choose cancer therapies.
To increase the value for participants in the project, Professor Caulfield established a coalition of 3,000 researchers worldwide and assisted the NHS in the creation of the National Genomic Test Directory. This will offer equitable access for 55 million people, depending on clinical need, to the appropriate genomic tests via a new National Genomic Medicine Service.
Canseq150 helps Canadian scientists map the Grizzly genome.
Among the largest predators in country, the Grizzly bear now has another claim to fame: the most complete genetic map for its species. Within 37 pairs of chromosomes composed of about 2.3 billion nucleotide base pairs, scientists have now revealed the location of 19,848 coding genes, 7,061 non-coding genes, 3,671 pseudo-genes, and more, within the Grizzly genome.
The Grizzly bear DNA was sequenced from a 20-year old male named Samson. He was found as an orphan in Alaska in 1998, when he was less than a year old, rescued and then raised at the Alaska Children’s Zoo. He now lives at the Toronto Zoo. The blood sample donated to the GSC was collected during a routine physical exam.
Published in the journal, Genes, the sequencing effort was performed at Canada’s Michael Smith Genome Sciences Centre at BC Cancer, a leading international centre for genomics and bioinformatics research. Dr. Steve Jones, GSC Co-Director and Head of Bioinformatics, was the Principal Investigator.
Canada’s Genomics Enterprise launchesCanSeq150 to lay the foundation for Canada’s next 150 years of science.
To commemorate the 150th Birthday of Canada in 2017 and to lay the foundation of Canadian excellence in research for the next 150 years, Canada’s Genomics Enterprise (CGEn) and its partners are embarking upon the Canada 150 Sequencing Initiative (CanSeq150). The aim is to sequence 150 new genomes to support sequence-based genomics research in Canada by enabling future research in biodiversity and conservation, applications in breeding and biomedicine, as well as technology development, across Canada.
The Personal Genome Project was supposed to revolutionize medicine, but the results reveal how much we still have to learn. Carolyn Abraham looks at the risk of misleading results as DNA testing enters mainstream medicine.
To support a new era of Canadian genome research, in 2014 Canada’s Foundation for Innovation (CFI) and its partners invested $58M in Canada’s Genomics Enterprise (CGEn), building an unprecedented sequencing and informatics capacity to decode genomes. CGEn linked three nationally funded centres in Toronto (The Centre for Applied Genomics), Montreal (McGill University and Genome Quebec Innovation Centre) and Vancouver (Canada’s Michael Smith Genome Science Centre). Furthermore, in 2017, an additional $32M were invested in CGEn through the CFI Major Science Initiative. CGEn, for the first time, built a coordinated framework for open access and collaborative genome sequencing across Canada.