DACO-main

HostSeq Data Access Compliance Office (DACO)

The Data Access Compliance Office (DACO) handles requests from scientists for access to controlled data from HostSeq (see controlled access data types here).

TO SUBMIT AN APPLICATION FOR DATA ACCESS, CLICK HERE

OVERVIEW

Data from the CGEn HostSeq Databank will be made available through open (aggregate) and controlled-access tiers, based on the type of data, its sensitivity and the specifications of the contributing collection.

Further information about the Databank Governance Framework can be found here.

  1. AIM
    The goal of the HostSeq Databank (‘HostSeq’) is to create: a unique, collaborative research infrastructure with the mission to conduct the whole genome sequencing (“WGS”) of 10,000 human genomes of Canadian affected by COVID-19, using Biological Samples provided by research participants; and, enable data sharing on COVID-19 and other health outcomes.

  2. GENERAL
    Data access and release under the controlled access tiers will be overseen by the HostSeq Independent Data Access Compliance Office (DACO). The role of the DACO is to receive access requests for projects proposing to use controlled-access data. The DACO assesses feasibility of the proposal, reviews and approves, conditionally approves or denies the request, according to criteria set here.

    For the purposes of health-related research on COVID-19 and other health outcomes, the CGEn HostSeq Databank allows free-of-charge access for academic research to the dataset of whole genome sequences and associated clinical data generated for the HostSeq Project, for the purposes of health-related research on COVID-19 and other health outcomes. 

    *The HostSeq Databank Rules and Policies will be amended and updated from time to time.

  3. DATA ACCESS
    Qualified researchers may apply to become a user of the HostSeq Databank by applying for data access through the HostSeq DACO, as described on the Application Process page. Applicants should make sure to provide all of the information requested in the application form. Partnered-researchers, that is, researchers who have contributed data to HostSeq can undergo an expedited controlled-access review.

    Once personal login information is provided, individuals are to continuously update their profile in the case of any changes relating to employment, or positions. If there are any changes in research projects or experimental designs, the DACO needs to be contacted immediately.

    HostSeq Databank users shall share results in accordance with applicable policies outlined in the HostSeq Publication & Acknowledgment Policy.

    The User may terminate his or her HostSeq Databank usage by written notice of resignation to the DACO.

  4. DACO COMPOSITION
    The DACO is composed of independent members who are not related to CGEn or its day-to-day activities and will include experts in Information Technology; the legal/ethical aspects of genomic research, data sharing, privacy and data protection; patient interest; and,  bioinformatics.

    Current HostSeq DACO members are:

    Holly Longstaff (Chair)
    Director, Privacy and Access, PHSA Research and New Initiatives
    Provincial Health Services Authority
    Simon Fraser University

    David Buckeridge
    Senior Scientist, RI-MUHC
    Metabolic Disorders and Complications Program
    Centre for Outcomes Research and Evaluation
    Professor, Department of Epidemiology and Biostatistics,
    Faculty of Medicine and Health Sciences, McGill University, 
    Department of Medicine, Division of Clinical Epidemiology, MUHC

    Jessica Denis
    Investigator, BC Children’s Hospital 
    Assistant Professor, Faculty of Medicine, Department of Medical Genetics
    The University of British Columbia 

    Chris McMaster
    Christopher R. McMaster, PhD, FCAHS
    Scientific Director / Directeur Scientifique
    CIHR Institute of Genetics / IRSC Institut de Génétique
    Government of Canada / Gouvernement du Canada
    and, Professor of Pharmacology, Dalhousie University

  5. CONTROLLED ACCESS
    All data access to HostSeq controlled data shall be related to the approved research project(s), to ensure compatibility with the objectives of the HostSeq Databank. Any project must be approved before the data is accessed. HostSeq Databank users shall use their access solely for the purpose of the research in which they participate, and for which they have been approved by the DACO.

  6. PUBLICATION POLICY
    CGEn HostSeq Databank users must comply with the HostSeq Publication & Acknowledgment Policy. Authorship and co-authorship of any publication or output should be defined in accordance with the guidelines issued by the International Committee of Medical Journal Editors (ICMJE) and as outlined in the HostSeq Publication Policy.

TO SUBMIT AN APPLICATION FOR DATA ACCESS, CLICK HERE